How and Why Do Lipid Droplets Accumulate in Gastric Epithelial Neoplasms?
نویسندگان
چکیده
Under the endoscopic observation with magnification endoscopy and narrow-band imaging, one of the novel findings in gastric neoplasms is white opaque substance (WOS), which is a manifestation of intracellular accumulation of lipid droplets. To elucidate the significance of this WOS formation, detailed lipid metabolism should be understood in gastric membranes. Recently, expression profiles of lipid-metabolism-associated genes in gastric tumor and non-tumor mucosa were investigated and reported. In this article, we explain the lipid accumulation and disturbance of lipid metabolism in gastric neoplasms.
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